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Research papers on Cognitive behavioral therapy

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  1. Evaluation of Cognitive Behavioral Therapy on Improving Pain, Fear Avoidance, and Self-Efficacy in Patients with Chronic Low Back Pain: A Systematic Review and Meta-Analysis

    Jia-Jia Yang, W. Lo, Fu-Ming Zheng, et al. · 2022 · Pain Research & Management · 124 citations

    Background Cognitive-behavioral therapy (CBT) is commonly adopted in pain management programs for patients with chronic low back pain (CLBP). However, the benefits of CBT are still unclear. Objectives This review investigated the effectiveness of CBT on pain, disability, fear avoidance, and self-efficacy in patients with CLBP. Methods Databases including PubMed, EMBASE, Web of Science, Cochrane Library, and PsycINFO were searched. RCTs examining the effects of CBT in adults with CLBP were included. The data about the outcome of pain, disability, fear avoidance, and self-efficacy were retained. Subgroup analysis about the effects of CBT on posttreatment was conducted according to CBT versus c

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  2. Comparative efficacy of onsite, digital, and other settings for cognitive behavioral therapy for insomnia: a systematic review and network meta-analysis

    L. Simon, L. Steinmetz, B. Feige, et al. · 2023 · Scientific Reports · 101 citations

    Given the limited availability and accessibility of onsite cognitive behavioral therapy for insomnia (CBT-I), other CBT-I settings, such as internet-delivered CBT-I (iCBT-I), have been proposed. The primary aim of the study was to compare the efficacy of available CBT-I settings on insomnia severity. A systematic review and frequentist network meta-analysis of available CBT-I settings was performed. PsycINFO, PsycARTICLES, MEDLINE, PubMed, and CINAHL were searched for randomized controlled trials (RCTs) investigating any CBT-I settings in adults with insomnia disorder. The systematic literature search (3851 references) resulted in 52 RCTs. For the primary outcome insomnia severity, all exami

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  3. Efficacy and acceptability of cognitive-behavioral therapy and serotonin reuptake inhibitors for pediatric obsessive-compulsive disorder: a network meta-analysis.

    Matti Cervin, Joseph F. McGuire, Johann M. D'Souza, et al. · 2024 · Journal of child psychology and psychiatry, and allied disciplines · 37 citations

    BACKGROUND Cognitive-behavioral therapy (CBT) and serotonin reuptake inhibitors (SRIs) are recommended treatments for pediatric obsessive-compulsive disorder (OCD), but their relative efficacy and acceptability have not been comprehensively examined. Further, it remains unclear whether the efficacy of in-person CBT is conserved when delivered in other formats, such as over telephone/webcam or as Internet-delivered CBT (ICBT). METHODS PubMed, PsycINFO, trial registries, and previous systematic reviews were searched for randomized controlled trials (RCTs) comparing CBT (in-person, webcam/telephone-delivered, or ICBT) or SRIs with control conditions or each other. Network meta-analyses were c

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  4. Long-Term Efficacy of Internet-Based Cognitive Behavioral Therapy Self-Help Programs for Adults With Depression: Systematic Review and Meta-Analysis of Randomized Controlled Trials

    Megi Mamukashvili-Delau, N. Koburger, Sandra Dietrich, et al. · 2023 · JMIR Mental Health · 37 citations

    Background Depression is a worldwide mental disorder and a leading cause of disability. Many people with depression do not want to take medication or have the motivation to seek psychotherapy treatment for many reasons. Guided internet-based self-help programs may be a promising solution for addressing these issues. This kind of intervention has proven to be effective in reducing depression symptoms on a short-term scale. However, as treatment often is a long-term rehabilitation process, it is important to examine not only the short-term effects of internet-based cognitive behavioral therapy (iCBT) self-help treatment but also the follow-up or long-term efficacy of this kind of intervention.

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  5. The efficacy of cognitive behavioral therapy for mental health and quality of life among individuals diagnosed with cancer: A systematic review and meta‐analysis

    Alexander T Dils, Kathryn O'Keefe, Nada Dakka, et al. · 2024 · Cancer Medicine · 28 citations

    It has long been documented that cognitive behavioral therapy (CBT) has positive impacts on improving mental health (MH) and quality of life (QoL) in the general population, but investigations on its effect on cancer survivors remain limited, especially for QoL outcomes. The purpose of this meta‐analysis is to investigate the effects of CBT as compared to control on cancer patients' MH and QoL outcomes. Control is defined in this study as standard therapy, waitlist control, and active/alternative therapy.

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  6. Efficacy and Acceptance of Cognitive Behavioral Therapy in Adults with Chronic Fatigue Syndrome: A Meta-analysis

    Frederic Maas Genannt Bermpohl, Ann-Cathrin Kucharczyk-Bodenburg, Alexandra Martin · 2024 · International Journal of Behavioral Medicine · 26 citations

    The systematic aggregation of research on cognitive behavioral therapy (CBT) in chronic fatigue syndrome (CFS) needs an update. Although meta-analyses evaluating interventions typically focus on symptom reduction, they should also consider indicators of treatment acceptability, e.g., drop-out rates. Randomized controlled trials (RCTs) investigating CBT in adults with CFS compared to inactive and non-specific control groups were included. First, efficacy was examined, considering fatigue, depression, anxiety, and perceived health. Secondly, drop-out rates through different trial stages were analyzed: Non-completion of all mandatory sessions, drop-out (primary study definition), treatment refu

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  7. The efficacy of cognitive behavioral therapy for insomnia in adolescents: a systematic review and meta-analysis of randomized controlled trials

    Zheng-Yang Mei, Chen-Yi Cai, Shu-Lai Luo, et al. · 2024 · Frontiers in Public Health · 23 citations

    Objective The objective of this systematic review and meta-analysis was to evaluate the overall efficacy of cognitive behavioral therapy for insomnia (CBT-I) in treating insomnia in adolescents, and to examine the efficacy of CBT-I on different sleep-related outcomes in this population. Methods Randomized controlled trials (RCTs) of CBT-I on insomnia in adolescents were identified using electronic databases and manual searches. The Revised Cochrane risk-of-bias tool for randomized trials (RoB 2) was used to assess risk of bias in RCTs. A standardized mean difference (SMD) with a 95% confidence interval (CI) was used to combine effect sizes. A sensitivity analysis was performed for each outco

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  8. Efficacy of cognitive behavioral therapy in treating repetitive negative thinking, rumination, and worry – a transdiagnostic meta-analysis

    K. Stenzel, Joshua Keller, Lukas Kirchner, et al. · 2025 · Psychological Medicine · 21 citations

    Abstract Repetitive negative thinking (RNT) is a transdiagnostic process associated with the onset, maintenance, and risk of relapse of various mental disorders. However, previous research syntheses addressing the effect of cognitive behavioral therapy (CBT) on RNT are limited to specific diagnoses, treatments, or RNT constructs (transdiagnostic RNT, worry, rumination). In the present meta-analysis, we integrate findings from randomized controlled trials (RCTs) of CBT on RNT across diagnoses, intervention types, and RNT constructs. We investigate the following questions: What is the overall transdiagnostic efficacy of CBT interventions on all post-treatment RNT outcomes? Which RNT construct

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  9. The efficacy of internet-based cognitive behavioral therapy for adult binge spectrum eating disorders: A meta-analysis.

    Jian Zhong, Yi-Han Zhang, Yifan Sun, et al. · 2024 · Journal of affective disorders · 18 citations

    OBJECTIVE Internet-Based Cognitive Behavioral Therapy (iCBT) is an innovative modality of cognitive-behavioral intervention that presents a promising therapeutic strategy for individuals diagnosed with binge spectrum eating disorders. This study employed a meta-analysis methodology to assess the clinical effectiveness and acceptability of iCBT. METHODS We conducted searches in databases such as PubMed, Embase, Web of Science, Cochrane Library, and PsycINFO, collecting literature that met the inclusion criteria until August 5, 2023. RESULTS A comprehensive analysis was conducted, encompassing a total of 11 randomized controlled studies that satisfied the predetermined criteria for inclusi

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  10. Efficacy of cognitive behavioral therapy for anxiety and depression in Parkinson’s disease patients: an updated systematic review and meta-analysis

    A. Alnajjar, M. Abouelmagd, Abdulrahman Krayim, et al. · 2024 · Neurological Sciences · 16 citations

    Parkinson’s disease (PD) patients often experience non-motor symptoms like depression and anxiety, significantly impacting their quality of life. With the limited effectiveness of pharmacological treatments, effective non-pharmacological interventions are needed. This systematic review and meta-analysis aimed to evaluate the efficacy of cognitive-behavioral therapy (CBT) in reducing depression and anxiety symptoms in PD patients. Randomized controlled trials (RCTs) exploring CBT's effectiveness for depression and anxiety in PD patients were included. Studies published until April 2023 were identified from PubMed, Web of Science, and Scopus. Methodological quality was assessed using the Risk

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  11. The Efficacy of Individual Cognitive Behavioral Therapy for Eating Disorders: A Meta‐Analysis of Randomized Controlled Trials

    Jana Bruns, Marieke Meier, Katrin Jansen · 2025 · The International Journal of Eating Disorders · 14 citations

    ABSTRACT Background This meta‐analysis aims to provide an update on the efficacy of individual cognitive behavioral therapy (CBT) for eating disorders (EDs) in the light of recent advances in the field, particularly the emergence of new approaches like self‐help. Method We conducted multivariate multilevel meta‐analyses using data from 42 randomized controlled trials to evaluate the efficacy of individual CBT for anorexia nervosa, bulimia nervosa, binge‐eating disorder, and mixed eating disorder samples. Outcomes included ED pathology, the frequency of binge eating and compensatory behaviors, and body mass index. The type of comparison group, treatment format, treatment duration, baseline ED

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  12. Efficacy of eHealth Versus In-Person Cognitive Behavioral Therapy for Insomnia: Systematic Review and Meta-Analysis of Equivalence

    S. Knutzen, D. Christensen, P. Cairns, et al. · 2024 · JMIR Mental Health · 13 citations

    Background Insomnia is a prevalent condition with significant health, societal, and economic impacts. Cognitive behavioral therapy for insomnia (CBTI) is recommended as the first-line treatment. With limited accessibility to in-person–delivered CBTI (ipCBTI), electronically delivered eHealth CBTI (eCBTI), ranging from telephone- and videoconference-delivered interventions to fully automated web-based programs and mobile apps, has emerged as an alternative. However, the relative efficacy of eCBTI compared to ipCBTI has not been conclusively determined. Objective This study aims to test the comparability of eCBTI and ipCBTI through a systematic review and meta-analysis of equivalence based on

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  13. Efficacy of cognitive behavioral therapy for musculoskeletal pain: a systematic review and meta-analysis

    Xianjun Liu, Wenxue Yuan, Xinman Gao, et al. · 2026 · Frontiers in Psychology · 10 citations

    Background Chronic musculoskeletal pain is a prevalent condition that causes substantial personal and societal burden, yet the effectiveness of non-pharmacological interventions remains debated. Cognitive behavioral therapy (CBT) and CBT-oriented cognitive-based interventions have been increasingly applied to pain management, but evidence has been fragmented across populations and treatment modalities. This study aimed to provide an updated synthesis of randomized controlled trials (RCTs) evaluating the efficacy of CBT for chronic musculoskeletal pain. Methods We conducted a systematic search of PubMed, Web of Science, Scopus, Embase, PsycINFO, and the Cochrane Library. Eligible studies were

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  14. The Efficacy of Internet-Based Cognitive Behavioral Therapy for Patients With Breast Cancer: A Systematic Review and Meta-Analysis

    Li-Hong Yang, Shujie Hao, D. Tu, et al. · 2024 · Integrative Cancer Therapies · 9 citations

    Objective: To systematically review and analyze the effects of Internet-based cognitive behavioral therapy (ICBT) on physical, psychological, and daily life outcomes in patients with breast cancer. Methods: Relevant studies were retrieved from Wanfang, CBM, CNKI, CINAHL, PsycINFO, Web of Science, The Cochrane Central Register of Controlled Trials, Embase and PubMed from inception to December 2023. Two independent authors conducted the literature search and data extraction. The Cochrane bias risk assessment tool was used to evaluate the included studies for methodological quality, and the data analysis was performed using Stata (Version 15.0). Results: Among 700 records, 11 randomized control

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  15. Efficacy of Cognitive Behavioral Therapy for Kinesiophobia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

    Shuyi Zhu, Yan-Xin Xu, Lin Wang, et al. · 2025 · Journal of Pain Research · 8 citations

    Background Kinesiophobia presents a significant barrier to rehabilitation across multiple conditions. While cognitive behavioral therapy (CBT) holds potential for addressing phobic responses, its specific efficacy against kinesiophobia requires clarification. Purpose To systematically evaluate CBT’s efficacy in reducing kinesiophobia among adults. Methods Following Cochrane guidelines, two independent reviewers searched six international databases (PubMed, Cochrane Library, Embase, EBSCO, Web of Science, Scopus) and four Chinese databases (SinoMed, CNKI, VIP, WanFang) for randomized controlled trials (RCTs) on CBT interventions targeting kinesiophobia, from inception through November 2024. I

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  16. Efficacy of Cognitive Behavioral Therapy and Acceptance- and Mindfulness-Based Treatments in Adults with Bodily Distress: A Network Meta-Analysis

    Frederic Maas Genannt Bermpohl, Alexandra Martin · 2025 · Psychotherapy and Psychosomatics · 7 citations

    Abstract Introduction: Many physical complaints cause long-term bodily distress. Meta-analyses show that cognitive behavioral therapy (CBT) and acceptance- and mindfulness-based treatments (AMBT) reduce somatic symptom severity, but evidence on differential efficacy is limited. This study evaluates the efficacy of CBT and AMBT for bodily distress (e.g., somatoform disorders, functional somatic syndromes, and related disorders). Methods: A network meta-analysis of randomized controlled trials on adults with bodily distress compared CBT and AMBT either directly or with nonspecific control groups. Cohen’s d based on between-group effect sizes was aggregated using a random effects model. Primary

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  17. Efficacy, User Engagement, and Acceptability of Cognitive Behavioral Therapy–Oriented Psychological Chatbots for Adults With Depressive and/or Anxiety Symptoms: Systematic Review and Meta-Analysis of Randomized Controlled Trials

    Bingyan Gong, Ni-Sha Yao, Hangxin Xie, et al. · 2025 · Journal of Medical Internet Research · 5 citations

    Abstract Background Cognitive behavioral therapy (CBT) is the most examined psychotherapy for depression and anxiety, but delivery faces significant barriers such as limited access, cost, and time constraints. CBT-oriented psychological chatbots offer a promising means of addressing these challenges. Yet, their overall efficacy, user engagement, and acceptability have not been systematically synthesized. Objective This study aimed to evaluate the efficacy, user engagement, and acceptability of CBT-oriented chatbots for adults with depressive and/or anxiety symptoms. Methods A systematic search of 9 databases, including PubMed, Cochrane Central Register of Controlled Trials, Embase, Web of Sc

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