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Research papers on Neuroplasticity and learning

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  1. Augmenting NMDA receptor signaling boosts experience-dependent neuroplasticity in the adult human brain

    Jennifer K. Forsyth, Peter Bachman, Daniel H. Mathalon, et al. · 2015 · Proceedings of the National Academy of Sciences · 78 citations

    Significance: Experience-dependent plasticity is the capacity of the brain to undergo changes following environmental input and use, and is a primary means through which the adult brain enables new behavior. In the current study, we provide evidence that enhancing signaling at the glutamate N -methyl- d -aspartate receptor (NMDAR) can enhance the mechanism underlying many forms of experience-dependent plasticity (i.e., long-term potentiation of synaptic currents) and also enhance experience-dependent learning in healthy adult humans. This suggests exciting possibilities for manipulating plasticity in adults and has implications for treating neurological and neuropsychiatric disorders in whic

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  2. Functional and Dysfunctional Neuroplasticity in Learning to Cope with Stress

    Simona Cabib, Paolo Campus, David Conversi, et al. · 2020 · Brain Sciences · 33 citations

    In this brief review, we present evidence of the primary role of learning-associated plasticity in the development of either adaptive or maladaptive coping strategies. Successful interactions with novel stressors foster plasticity within the neural circuits supporting acquisition, consolidation, retrieval, and extinction of instrumental learning leading to development of a rich repertoire of flexible and context-specific adaptive coping responses, whereas prolonged or repeated exposure to inescapable/uncontrollable stressors fosters dysfunctional plasticity within the learning circuits leading to perseverant and inflexible maladaptive coping strategies. Finally, the results collected using a

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  3. Brain-Inspired Multisensory Learning: A Systematic Review of Neuroplasticity and Cognitive Outcomes in Adult Multicultural and Second Language Acquisition

    Evgenia Gkintoni, Stephanos P. Vassilopoulos, Georgios Nikolaou · 2025 · Biomimetics · 32 citations

    Background: Multicultural education and second-language acquisition engaged neural networks, supporting executive function, memory, and social cognition in adulthood, represent powerful forms of brain-inspired multisensory learning. The neuroeducational framework integrates neuroscience with pedagogical practice to understand how linguistically and culturally rich environments drive neuroplasticity and cognitive adaptation in adult learners. Objective: This systematic review synthesizes findings from 80 studies examining neuroplasticity and cognitive outcomes in adults undergoing multicultural and second-language acquisition, focusing on underlying neural mechanisms and educational effective

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  6. Neuroplasticity And Adult Learning: Can An Old Dog Learn New Tricks?

    Andriana Eliadis · 2024 · Educational Administration: Theory and Practice

    Adult learning has always remained a topic of discussion among researchers. Thus, this study aimed to extend this debate in the context of literature. This is a qualitative literature-based review that has focused on prior studies. Following the comprehensive inclusion and exclusion criteria, the data was gathered from academic journals and books. The results reported a strong connection between neuroplasticity and adult learning. They negated the old dogma that the brain's cells never regenerate, and adults cannot learn as effectively as when they were young. The findings highlighted that adults taking a healthy and nutritional diet and exercising regularly can learn as effectively as the y

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  7. The Impact of Digital Technologies and AI on Adult Learning: From Digital Literacy to Neuroplasticity

    Yana Topolnyk, Roman Gurevych, Ihor Debenko, et al. · 2025 · BRAIN. Broad Research in Artificial Intelligence and Neuroscience

    This article explores the urgent issue of developing digital skills and stimulating neuroplasticity in adults during rapid digital transformation. It examines how information and communication technologies (ICT) and artificial intelligence (AI) contribute to effective adult education. The article analyses the theoretical foundations of digital literacy and neuroplasticity. It also discusses practical strategies for enhancing these areas through ICT and AI. To support this analysis, the study applies several research methods. These include a theoretical review of scientific literature, comparative analysis, and case study approaches. The methods are used to investigate real-life examples of a

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  9. Neuroplasticity in Adult Learning: Underlying Mechanisms and Therapeutic Applications

    Shyma Kareem, Anand Bhuyar · 2026 · Journal of Artificial Intelligence and Information

    This review examines the current understanding of neuroplasticity in adult learning, focusing on cellular mechanisms, therapeutic applications, and implications for rehabilitation and education. Recent advances in neuroscience have revolutionized our understanding of the brain's capacity for change throughout adulthood, challenging traditional notions of fixed neural architecture. This paper synthesizes findings from molecular studies, clinical trials, and cognitive research to present a comprehensive overview of adult neuroplasticity and its practical applications in therapeutic contexts. The scope of this review encompasses research conducted between 2015 and 2024, highlighting significant

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